Phospholipids are at the heart and origin of life on this planet. The possibilities in terms of phospholipid self-assembly and biological functions seem limitless. Nonetheless, nature exploits only a small fraction of the available chemical space of phospholipids. Using chemical synthesis, additional, artificial phospholipid structures become accessible, and the study of their biophysics may reveal unprecedented properties.
In this presentation, we journey away from standard spherical bilayer liposomes into the world of developable surface liposomes such as liposomal cubes, and liposomal sphericons. And we will have a look at mechanosensitive liposomes and their potential in targeted drug delivery for the treatment of heart attacks and stroke.
